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Title of the Invention
Preventive and/or ameliorative agent for diseases, stamina enhancement agent, anti-fatigue agent, and pharmaceutical and food and drink using them
Filing Date: November 19, 2010 
Patent applicant: TFK Co., Ltd.,
Applicant countries: Hong Kong, China, Great Britain, German, France
Registration Date: May 15th, 2015 (Japan) July 1st, 2015 (China) December 4th, 2015 (Hong Kong) March 30th, 2016(Great Britain, German, France)

 

Excerpt of original text

[0070]
As mentioned above, the preventive and/or ameliorative agent of the present invention is a preventive and/or ameliorative agent for at least one disease selected from the group consisting of inflammatory diseases, allergic diseases, and autoimmune diseases, the preventive and/or ameliorative agent including: at least one of a purple non-sulfur bacteria and a culture material obtained by culturing the purple non-sulfur bacteria, wherein the purple non-sulfur bacteria. As mentioned above, the stamina enhancement agent and the anti-fatigue agent of the present invention each includes: at least one of a purple non-sulfur bacteria and a culture material obtained by culturing the purple non-sulfur bacteria, and the purple non-sulfur bacteria.


[0141]
Examples of the inflammatory diseases include inflammatory diseases of internal organs, skins, joints, a central nervous system, and they are not particularly limited. Specific examples thereof include inflammatory bowel diseases such as ulcerative colitis and a Crohn's disease, inflammatory skin diseases such as psoriasis and skin inflammation, encephalitis, hepatitis, nephritis, pneumonia, bronchitis, vasculitis, meningitis, thyroiditis, diabetes, inflammatory bile diseases, and cancers involving inflammations, and they are not particularly limited. Accompanying the exertion of anti-inflammatory effects in preventing and/or ameliorating the inflammatory diseases, effects of relieving pain associated with an inflammation is also exerted.


[0142]
The allergic diseases are not particularly limited, and examples thereof include Type I allergic diseases, Type II allergic diseases, Type III allergic diseases, Type IV allergic diseases, and Type V allergic diseases. The allergic diseases are preferably the Type I allergic diseases or the Type IV allergic diseases. The Type I allergic diseases are not particularly limited, and specific examples thereof include urticaria, pollinosis, asthma, a PIE syndrome, atopic dermatitis, allergic rhinitis, allergic conjunctivitis, a food allergy, a drug allergy, and anaphylaxis. The Type IV allergic diseases are not particularly limited, and specific examples thereof include contact dermatitis and the like.


[0143]
The autoimmune diseases are not particularly limited, and examples thereof include rheumatoid arthritis, erythematosus, multiple sclerosis, systemic sclerosis, psoriatic arthritis, an infectious disease, and Sjogren's syndrome.


[0144]
It is only necessary that the preventive and/or ameliorative agent of the present invention can prevent and/or ameliorate at least one disease of inflammatory diseases, allergic diseases, and autoimmune diseases, and it may prevent and/or ameliorate various diseases. The preventive and/or ameliorative agent of the present invention further may prevent and/or ameliorate other diseases. The other diseases are not particularly limited, and examples thereof include cardiovascular diseases, cancers, and infectious diseases.


[0145]
The cardiovascular diseases are not particularly limited, and examples thereof include hypertension, myocardial infarction, angina pectoris, and arteriosclerosis.


[0146]
The cancers are not particularly limited, and examples thereof include a lung cancer, a liver cancer, a gastrointestinal cancer, a renal cancer, a pancreatic cancer, a thyroid cancer, a prostate cancer, an ovarian cancer, an uterine cancer, and a bone cancer.


[0147]
The infectious diseases are not particularly limited, and examples thereof include infectious diseases caused by various virus such as hepatitis virus, influenza virus, and human immunodeficiency virus and infectious diseases caused by MRSA, hemolytic streptococcus, and mycoplasma.


[0148]
<Pharmaceutical>
[0149]
The first pharmaceutical of the present invention is not at all limited except that it is for preventing or ameliorating at least one disease selected from the group consisting of inflammatory diseases, allergic diseases, and autoimmune diseases and contains the preventive and/or ameliorative agent of the present invention. The first pharmaceutical of the present invention further may contain at least one of the stamina enhancement agent of the present invention and the anti-fatigue agent of the present invention. The second pharmaceutical of the present invention is not at all limited except that it contains at least one of the stamina enhancement agent of the present invention and the anti-fatigue agent of the present invention. The second pharmaceutical of the present invention further may contain the preventive and/or ameliorative agent of the present invention. Hereinafter, the first pharmaceutical of the present invention and the second pharmaceutical of the present invention are collectively also referred to as merely a “pharmaceutical”. In the present invention, the pharmaceutical encompasses a pharmaceutical and a quasi drug. The pharmaceutical of the present invention further may contain other preventive and/or ameliorative agents, other stamina enhancement agents, and other anti-fatigue agents. The other preventive and/or ameliorative agents are not particularly limited, and examples thereof include preventive and/or ameliorative agents for the above-mentioned other diseases. The other stamina enhancement agents and the other anti-fatigue agents are not particularly limited.


[0151]
<Food and Drink>
[0152]
The first food and drink of the present invention is not at all limited except that it has a function to prevent and/or ameliorate at least one disease selected from the group consisting of inflammatory diseases, allergic diseases, and autoimmune diseases and contains the preventive and/or ameliorative agent of the present invention. The first food and drink of the present invention further may contain at least one of the stamina enhancement agent of the present invention and the anti-fatigue agent of the present invention. The second food and drink of the present invention is not at all limited except that it contains at least one of the stamina enhancement agent of the present invention and the anti-fatigue agent of the present invention. The second food and drink of the present invention further may contain the preventive and/or ameliorative agent of the present invention. Hereinafter, the first food and drink of the present invention and the second food and drink of the present invention are collectively also referred to as merely “food and drink”. In the present invention, food and drink encompasses common food and food with health claims. The common food is not particularly limited, and examples thereof include processed grain products, processed vegetable products, processed fruit products, processed meat products, processed fishery products, dairy products, drinks, and health food. The food and drink of the present invention may contain the preventive and/or ameliorative agent, the stamina enhancement agent, and the anti-fatigue agent as materials or additives, for example. The processed grain products are not particularly limited, and examples thereof include flour, rice flour, cereal bars, senbei (rice crackers), arare (rice cake cubes), and cookies. The processed vegetable products are not particularly limited, and examples thereof include vegetable pastes, dried vegetables, and vegetable soups. The processed fruit products are not particularly limited, and examples thereof include pureed fruits and dried fruits. The processed meat products are not particularly limited, and examples thereof include hams, bacon, and sausages. The processed fishery products are not particularly limited, and examples thereof include tsukudani (foods boiled down in soy sauce), enkanbutsu (salted-dried foods), fish sausages, hanpen (boiled fish paste cake), kamaboko (steamed fish paste cake), and chikuwa (tube-shaped fish paste cake). The dairy products are not particularly limited, and examples thereof include milk beverages, yoghurts, ice creams, and cheeses. The drinks are not particularly limited, and examples thereof include soft drinks, green tea, black tea, and coffee. The food with health claims is generally also called functional food. Examples of the food with health claims include food for specified health use and food with nutrient function claims.

INDUSTRIAL APPLICABILITY
 [0236] As described above, the purple non-sulfur bacteria of the present invention has various effects of suppressing ulcer formation, suppressing inflammatory cell invasion, suppressing swelling of a mucosal epithelium, regenerating an epithelium, suppressing hepatic necrosis, accelerating swelling of liver cell, reducing amounts of IgE and histamine in a serum, suppressing Th2 cytokine secretion, ameliorating a Th1/Th2 imbalance, suppressing an allergic reaction, suppressing an autoimmune disease, enhancing stamina, anti-fatigue, and the like. The purple non-sulfur bacteria of the present invention can prevent and/or ameliorate at least one disease selected from the group consisting of inflammatory diseases, allergic diseases, and autoimmune diseases, can enhance stamina, and can suppress fatigue. The purple non-sulfur bacteria of the present invention has high safety, so that it can be administered for the purpose of preventing diseases, and also, it can be administered for a long term. Thus, according to the present invention, a preventive and/or ameliorative agent, a stamina enhancement agent, an anti-fatigue agent, a pharmaceutical, and food and drink, being useful in preventing and/or ameliorating at least one disease selected from the group consisting of inflammatory diseases, allergic diseases, and autoimmune diseases, enhancing stamina, and anti-fatigue and having high safety, can be provided, and application ranges thereof are not limited and wide.

 

 

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